Photo of Francesco Costanzo

Francesco Costanzo

Professor

Affiliation(s):

  • Engineering Science and Mechanics
  • Mechanical Engineering
  • Biomedical Engineering

W315 Millennium Science Complex

fxc8@psu.edu

814-863-2030

Personal or Departmental Website

Research Areas:

Brain Science and Neural Engineering; Dynamic Systems, Acoustics, and Vibrations; Multiscale and Multiphysics Modeling, Computational Analysis

Interest Areas:

Continuum thermodynamics; Mechanics of thin films; Time-dependent fracture and damage mechanics of composites; Micromechanics and homogenization of inelastic composites; Computational mechanics; Thermodynamics of interfaces; Large deformations.

 
 

 

Education

  • Laurea, Aeronautical Engineering, Politecnico di Milano, 1989
  • Ph D, Aerospace Engineering, Texas A&M University, 2003

Publications

Journal Articles

  • Priyanka A. Patki, Scott D Simon, Keefe B Manning and Francesco Costanzo, 2023, "Computational analysis of effects of clot length on acute ischemic stroke recanalization under different cyclic aspiration loading conditions", International Journal for Numerical Methods in Biomedical Engineering, e3667, pp. 1–15
  • Farshad Ghambari, Francesco Costanzo, David Hughes and Christian Peco Regales, 2020, "Phase-Field Modeling of Constrained Interactive Fungal Networks", Journal of the Mechanics and Physics of Solids, 145, pp. 104160-1–104160-21
  • Bryan C. Good, Francesco Costanzo, Scott D Simon and Keefe B Manning, 2020, "Hydrodynamics in Acute Ischemic Stroke Catheters Under Static and Cyclic Aspiration Conditions", Cardiovascular Engineering and Technology, 11, (6), pp. 689–698
  • Bugra Ayan, Nazmiye Celik, Zhifeng Zhang, Kui Zhou, Myoung Hwan Kim, Dishary Banerjee, Yang Wu, Francesco Costanzo and Ibrahim Ozbolat, 2020, "Aspiration-Assisted Freeform Bioprinting of Pre-Fabricated Tissue Spheroids in a Yield-Stress Gel", Communications Physics, 3, (1), pp. 183-1–183-14
  • Ravi T. Kedarasetti, Kevin L. Turner, Christina Echagarruga, Bruce Gluckman, Patrick Drew and Francesco Costanzo, 2020, "Functional Hyperemia Drives Fluid Exchange in the Paravascular Space", Fluids and Barriers of the CNS, 17, (1), pp. 52-1–52-25
  • Ravi T. Kedarasetti, Patrick Drew and Francesco Costanzo, 2020, "Arterial Pulsations Drive Oscillatory Flow of CSF but not Directional Pumping", Scientific Reports, 10, pp. 10:10102-1–10:10102-12
  • N. Goel, Francesco Costanzo and Srinivas A Tadigadapa, 2019, "Experimental Studies in Micromachined AT-Cut Quartz-Based Differential Vacuum Gauges", IEEE Sensors Journal, 19, (6), pp. 2047-2054
  • Rune Barnkob, Nitesh Nama, Liqiang Ren, Tony Jun Huang, Francesco Costanzo and Christian J. Kähler, 2018, "Acoustically Driven Fluid and Particle Motion in Confined and Leaky Systems", 9, (1), pp. 014027-1–014027-12
  • C Chen, S. Z. Zhang, Z. Mao, P. -H. Huang, Y. Jing, X. Guo, Francesco Costanzo and T J Huang, 2018, "Three-Dimensional Numerical Simulation and Experimental Investigation of Boundary-Driven Streaming in Surface Acoustic Wave Microfluidics", Lab on a Chip, 18, (23), pp. 3645-3654
  • Zhangming Mao, Peng Li, Mengxi Wu, Hunter Bachman, Nicolas Mesyngier, Xiasheng Guo, Sheng Liu, Francesco Costanzo and Tony Huang, 2017, "Enriching Nanoparticles via Acoustofluidics", ACS Nano, 11, (1), pp. 603-612
  • R. Acharya, B Evans, J Pitt, Francesco Costanzo and Kenneth K Kuo, 2017, "Coupling of Transient Thermal and Mechanical Stresses Computations in Graphite Nozzle Materials", International Journal of Energetic Materials and Chemical Propulsion, 16, (2), pp. 175-195
  • Yuliang Xie, Nitesh Nama, Peng Li, Zangming Mao, Po-Hsun Huang, Chenglong Zhao, Francesco Costanzo and Tony Huang, 2016, "Probing cell deformability via acoustically actuated bubbles", Small, 12, (7), pp. 902-910
  • Zhangming Mao, Yuliang Xie, Feng Guo, Liqiang Ren, Po-Hsun Huang, Yuchao Chen, Joseph Rufo, Francesco Costanzo and Tony Huang, 2016, "Experimental and numerical studies on standing surface acoustic wave microfluidics", Lab on a Chip, 16, (3), pp. 515-524
  • Z Mao, Y Xie, F Guo, L Ren, P-H Huang, Y Chen, J Rufo, Francesco Costanzo and Jun Huang, 2016, "Experimental and Numerical Studies on Standing Surface Acoustic Wave Microfluidics", Lab on a Chip, 16, (3), pp. 515-524
  • Y Xie, N. Nama, P Li, Z Mao, P-H Huang, C Zhao, Francesco Costanzo and Jun Huang, 2015, "Probing Cell Deformability via Acoustically Actuated Bubbles", Small, pp. 9
  • S Roy, L Heltai and Francesco Costanzo, 2015, "Benchmarking the Immersed Finite Element Method for Fluid-Structure Interaction Problems", Computers and Mathematics with Applications, 69, (10), pp. 1167-1188
  • N. Nama, R Barnkob, Z Mao, C J Kähler, Francesco Costanzo and Jun Huang, 2015, "Numerical Study of Acoustophoretic Motion of Particles in a PDMS Microchannel Driven by Surface Acoustic Waves", Lab on a Chip, 15, (12), pp. 2700-2709
  • Y Xie, C Chindam, N Nama, S Yang, M Lu, Y Zhao, J D Mai, Francesco Costanzo and Jun Huang, 2015, "Exploring Bubble Oscillation and Mass Transfer Enhancement in Acoustic-Assisted Liquid-Liquid Extraction with a Microfluidic Device", Scientific Reports, 5, pp. 12572 -1– 12572-9
  • N Nama, P H Huang, T J Huang and F Costanzo, 2014, "Investigation of Acoustic Streaming Patterns around Oscillating Sharp Edges", Lab on a Chip, 14, (15), pp. 2824-2836
  • Z Mao, F Guo, Y Xie, Z Yanhui, M I Lapsley, J DH Mai, F Costanzo and T J Huang, 2014, "Label-Free Measurements of Reaction Kinetics using a Droplet-Based Optofluidic Device", Journal of Laboratory Automation, 20, (1), pp. 17--24
  • Luca Heltai, Saswati Roy and Francesco Costanzo, 2014, "A Fully Coupled Immersed Finite Element Method for Fluid Structure Interaction via the {Deal.II} Library", Archive of Numerical Software, 2, (1), pp. 1-27
  • Francesco Costanzo and J. G. Brasseur, 2013, "The Invalidity of the Laplace Law for Biological Vessels and of Estimating Elastic Modulus from Total Stress vs. Strain: a New Practical Method", Mathematical Medicine & Biology
  • C. Chindam, N. Nama, M. I. Lapsley, Francesco Costanzo and T. J. Huang, 2013, "Theory and Experiment on Resonant Frequencies of Liquid-Air Interfaces Trapped in Microfluidic Devices", Journal of Applied Physics, 114
  • X. Ding, P. Li, S.-C. S. Lin, Z. S. Stratton, N. Nama, F. Guo, D. Slotcavage, X. Mao, J. Shi, Francesco Costanzo and T. J. Huang, 2013, "Surface Acoustic Wave Microfluidics", Lab on a Chip, 13, pp. 3626-3649
  • L. Heltai and Francesco Costanzo, 2012, "Variational Implementation of Immersed Finite Element Methods", Computer Methods in Applied Mechanics and Engineering, 229-232, pp. 110-127
  • T. A. Litzinger, P. Van Meter, C. M. Firetto, L. J. Passmore, C. B. Masters, S. R. Turns, G. L. Gray, Francesco Costanzo and S. E. Zappe, 2010, "A Cognitive Study of Problem Solving in Statics", Journal of Engineering Education, pp. 337-353
  • J. S. Pitt and Francesco Costanzo, 2009, "An Adaptive h-Refinement Algorithm for Local Damage Models", 2, pp. 1281-1300
  • D. K. Khalmanova and Francesco Costanzo, 2008, "A Space-Time Discontinuous Galerkin Finite Element Method for Fully Coupled Linear Thermo-Elasto-Dynamic Problems with Strain and Heat Flux Discontinuities", Computer Methods in Applied Mechanics and Engineering, 197, (13-16), pp. 1323-1342
  • S. T. Miller and Francesco Costanzo, 2008, "A numerical Verification for an Unconditionally Stable FEM for Elastodynamics", Computational Mechanics, 43, (2), pp. 223-237
  • Charles L. Randow, Gary L. Gray and Francesco Costanzo, 2006, "A Directed Continuum Model of Micro- and Nano-scale Thin Films", International Journal of Solids and Structures, 43, (5), pp. 1253-1275
  • Pedro C. Andia, Francesco Costanzo and Gary L. Gray, 2006, "A Classical Mechanics Approach to the Determination of the Stress-Strain Response of Particle Systems", Modelling and Simulation in Materials Science and Engineering, 14, pp. 741-757
  • Francesco Costanzo, Gary L. Gray and Pedro C. Andia, 2005, "On the Definitions of Effective Stress and Deformation Gradient for Use in MD: Hill's Macro-homogeneity and the Virial Theorem", International Journal of Engineering Science, 43, (7), pp. 533-555
  • Pedro C. Andia, Francesco Costanzo and Gary L. Gray, 2005, "A Lagrangian-Based Continuum Homogenization Approach Applicable to Molecular Dynamics Simulations", International Journal of Solids and Structures, 42, (24-25), pp. 6409-6432
  • Francesco Costanzo and Hao Huang, 2005, "Proof of unconditional stability for a single-field discontinuous Galerkin finite element formulation for linear elasto-dynamics", Computer Methods in Applied Mechanics and Engineering, 194, (18-20), pp. 2059-2076
  • Francesco Costanzo and Scott T Miller, , "An Arbitrary Lagrangian–Eulerian Finite Element Formulation for a Poroelasticity Problem Stemming from Mixture Theory", Computer Methods in Applied Mechanics and Engineering, 323, pp. 64–97
  • Nitesh Nama, Tony Huang and Francesco Costanzo, , "Acoustic Streaming: An Arbitrary Lagrangian–Eulerian Perspective", Journal of Fluid Mechanics, 825, pp. 600-630
  • Bryan C. Good, Scott D Simon, Keefe B Manning and Francesco Costanzo, , "Development of a Computational Model for Acute Ischemic Stroke Recanalization Through Cyclic Aspiration", Biomechanics and Modeling in Mechanobiology, 19, (2), pp. 761–778
  • Priyanka A. Patki and Francesco Costanzo, , "A Mixture Theory-Based Finite Element Formulation for the Study of Biodegradation of Poroelastic Scaffolds", Computational Mechanics, 66, (2), pp. 351–371
  • O. Oyekole, Scott D Simon, Keefe B Manning and Francesco Costanzo, , "Modeling Acute Ischemic Stroke Recanalization through Cyclic Aspiration", Journal of Biomechanics, 128, pp. 110721-1--110721-8
  • R. T. Kedarasetti, Patrick Drew and Francesco Costanzo, , "Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model", Fluids and Barriers of the CNS, 19, (1), pp. 34-1–34-24
  • N Nama, P-H Huang, Jun Huang and Francesco Costanzo, , "Investigation of Micromixing by Acoustically Oscillated Sharp-Edges", Biomicrofluidics, 10, pp. 17

Conference Proceedings

  • S. Roy, L. Heltai, C. S. Drapaca and Francesco Costanzo, 2013, "An Immersed Finite Element Method Approach for Brain Biomechanics", Conference Proceedings of the Society for Experimental Mechanics Series, Springer, New York, 5, pp. 79-86
  • Peggy Van Meter, Carla Firetto, Lucas J. Passmore, Francesco Costanzo, Gary L. Gray, Thomas A. Litzinger, Christine B. Masters and Stephen R. Turns, 2009, "Prompting Self-explanation to Improve Engineering Students' Problem Solving", Proceedings of the 13th Biennial Conference of the European Association for Research on Learning and Instruction---EARLI 2009
  • G. L. Gray and Francesco Costanzo, 2008, "A Problem-Centered Approach to Dynamics", Proceedings of the 2008 American Society for Engineering Education Annual Conference & Exposition, pp. 14
  • Francesco Costanzo and G. L. Gray, 2008, "A Structured Approach to Problem Solving in Statics and Dynamics: Assessment and Evolution", Proceedings of the 2008 American Society for Engineering Education Annual Conference & Exposition, pp. 10
  • Thomas Litzinger, Carlo Firetto, Lucas Passmore, Peggy Van Meter, Kelli Higley, Christine Masters, Francesco Costanzo, Gary L. Gray, Steve Turns and Jonna Kulikowich, 2008, "Identifying and Remediating Deficiencies with Problem-Solving in Statics", Proceedings of the 2008 American Society for Engineering Education Annual Conference & Exposition, pp. 18
  • Francesco Costanzo and Gary L. Gray, 2008, "Using Parametric Analysis to Incorporate Design into Sophomore-Level Dynamics", 2008 American Society for Engineering Education Annual Conference & Exposition
  • D. K. Khalmanova and Francesco Costanzo, 2006, "Discontinuous Space-Time Galerkin Finite Element Method in Linear Dynamic Fully Coupled Thermoelastic Problems with Strain and Heat Flux Discontinuities", ECCM-2006-III European Conference on Computational Mechanics, pp. 6
  • Gary L. Gray, Francesco Costanzo and Michael E. Plesha, 2005, "Problem Solving in Statics and Dynamics: A Proposal for a Structured Approach", Proceedings of the 2005 American Society for Engineering Education Annual Conference & Exposition, pp. 13
  • Gary L. Gray, Francesco Costanzo, Don Evans, Phillip Cornwell, Brian Self and Jill L. Lane, 2005, "The Dynamics Concept Inventory Assessment Test: A Progress Report and Some Results", Proceedings of the 2005 American Society for Engineering Education Annual Conference & Exposition, pp. 16
  • Gary L. Gray, Francesco Costanzo, Pedro C. Andia, Don Evans, Brian Self and Phillip J. Cornwell, 2005, "The Dynamics Concept Inventory Test as a Means of Assessing Curricular Innovations", Proceedings of McMat2005, the Joint ASME/ASCE/SES Conference on Mechanics and Materials

Research Projects

  • February 2016 - January 2021, "From Cells to Societies: Mechanisms by Which Microbial Parasites Control Hosts Phenotypes," (Sponsor: National Institute of General Medical Sciences).

Honors and Awards

  • 2020-21 BTAA Academic Leadership Program (ALP) Fellow, Big Ten Academic Alliance, June 2020 - April 2021

Service

Service to Penn State:

Service to External Organizations:

 


 

About

The Penn State Department of Engineering Science and Mechanics (ESM) is an internationally distinguished department that is recognized for its globally competitive excellence in engineering and scientific accomplishments, research, and educational leadership.

Our Engineering Science program is the official undergraduate honors program of the College of Engineering, attracting the University’s brightest engineering students. We also offer graduate degrees in ESM, engineering mechanics, engineering at the nano-scale, and an integrated undergraduate/graduate program.

Department of Engineering Science and Mechanics

212 Earth and Engineering Sciences Building

The Pennsylvania State University

University Park, PA 16802

Phone: 814-865-4523