CONTACT INFORMATION

Corina S. Drapaca, PhD
Assistant Professor, Department of Engineering Science and Mechanics
Member, Penn State Center for Neural Engineering
The Pennsylvania State University
313W Millennium Science Complex Building
University Park, PA 16802, USA
Phone: 814-867-2313
E-mail: csd12@psu.edu

DEGREES WITH FIELDS, INSTITUTION AND DATE

  • B.S. in Mathematics-Mechanics, Faculty of Mathematics - University of Bucharest, Romania, 1995.
  • M.S. in Applied Mathematics, Faculty of Mathematics - University of Bucharest, Romania, 1996.
  • Ph.D. in Applied Mathematics, Faculty of Mathematics - University of Waterloo, Canada, 2002.

PROFESSIONAL EXPERIENCE

  • 1996-1997: Teaching Assistant, Institute of Civil Engineering and Faculty of Mathematics, Bucharest.
  • 1997-2002: Teaching and Research Assistant, Faculty of Mathematics, University of Waterloo.
  • 2002-2004: Visiting Postdoctoral Fellow, Department of Radiology, University of California in San Francisco.
  • 2004-2005: Visiting Postdoctoral Fellow, Department of Applied Mathematics, University of Waterloo.
  • 2005-2006: Visiting Postdoctoral Fellow, Department of Physiology and Biomedical Engineering, Mayo Clinic.
  • 2007 - present: Assistant Professor, Department of Engineering Science and Mechanics, Pennsylvania State University.

RESEARCH INTERESTS

MATHEMATICAL MEDICINE:

  • Brain Neuro-mechanics (coupling the biochemistry and biomechanics of the brain)
  • Continuum Mechanics (new theoretical and analytical methods to describe multiple time and length scales phenomena, non-locality and damage)
  • Computational Mechanics (numerical methods for non-linear heat equation, reaction-diffusion equation, coupled hyperbolic-parabolic system of equations using finite difference, finite element, and generalized finite element methods)
  • Medical Image Processing (segmentation, registration, denoising/deblurring techniques)
  • Elastography and Inverse Problems (with the aim of improving computer-aided diagnosis and treatment outcome)
  • Tumor Classification and Growth Modeling

PUBLICATIONS

IN PREPARATION:

1. R. Shao, C.S. Drapaca, A Computational Study of the Coupling between the Spatiotemporal Dynamics and the Mechanics of the Cerebral Cortex.

2. S. Roy, L. Heltai, C.S. Drapaca, F. Costanzo, A Preliminary Study of Brain Biomechanics using the Immersed Finite Element Method: Application to Hydrocephalus.

3. D.L. Andre, B. Shanmugasundaram, C. Drapaca, B. Gluckman, A Study of Safety and Performance of Brain Stimulating Electrodes.

UNDER REVIEW:

4. D. Engels, A.E. Segall, C. Drapaca, An Inverse Method for Determining Temperature Dependent Thermophysical Properties based on a Remotely Measured Temperature History, Technical Brief, International Journal of Heat and Mass Transfer, December 2011.

5. A.E. Segall, C. Drapaca, D. Engels, T. Zhu, H. Yang, Direct and Inverse Solutions for Thermal- and Stress-Transients and the Analytical Determination of Boundary Conditions Using Remote Temperature or Strain Data, ASME Journal of Pressure Vessel Technology, December 2011.

JOURNAL PAPERS:

6. K.P. Wilkie, C.S. Drapaca, S. Sivaloganathan, A Mathematical Investigation of the Role of Intracranial Pressure Pulsations and Small Gradients in the Pathogenesis of Hydrocephalus, International Journal of Numerical Analysis and Modeling, Series B, Special Issue on Brain Neuro-Mechanics, vol. 3, no. 1 (2012): 36-51.

7. C.S. Drapaca, J.S. Fritz, A Mechano-Electrochemical Model of Brain Neuro-Mechanics: Application to Normal Pressure Hydrocephalus, International Journal of Numerical Analysis and Modeling, Series B, Special Issue on Brain Neuro-Mechanics, vol.3, no.1 (2012): 82-93.

8. A.J. Palocaren, C.S. Drapaca, Biomedical Modeling of Tumor Growth: Its Relevance to Glioma Research, International Journal of Numerical Analysis and Modeling, Series B, Special Issue on Brain Neuro-Mechanics, vol.3, no.1 (2012): 94-108.

9. J. Park, S.M. Shontz, C.S. Drapaca, A combined level set/mesh warping algorithm for tracking brain and cerebrospinal fluid evolution in hydrocephalic patients, Invited submission to Image-based Modeling and Mesh Generation (peer reviewed book chapter).

10. C.S. Drapaca, S. Sivaloganathan, The Fractional Model of Continuum Mechanics, Journal of Elasticity, DOI: 10.1007/s10659-011-9346-1; Published online after peer reviewed: June 2, 2011 (to also appear in paper issue).

11. K.P. Wilkie, C.S. Drapaca, S. Sivaloganathan, Aging Impact on the Brain Biomechanics with Application to Hydrocephalus, Mathematical Medicine and Biology, doi: 10.1093/imammb/dqr001; Published online after peer reviewed: March 10, 2011(to also appear in paper issue).

12. K.P. Wilkie, C.S. Drapaca, S. Sivaloganathan, A Nonlinear Fractional Derivative Model of Infant Hydrocephalus, Applied Mathematics and Computation, vol.217, no. 21 (2011): 8693-8704.

13. C.S. Drapaca, A. Palocaren, Biomechanical Modeling of Tumor Classification and Growth, Revue Roumanie des Sciences Techniques serie de Mechanique Apliquee, vol. 55, no.2 (2010): 115-124. (peer reviewed, in English)

14. J.G. Mandell, T. Neuberger, C.S. Drapaca, A.G. Webb, S.J. Schiff, The Dynamics of Brain and CSF Growth in Normal versus Hydrocephalic Mice: Laboratory Investigation, Journal of Neurosurgery Pediatrics vol.6 (2010): 1-10.

15. C.S. Drapaca, A Novel Mechanical Model for Magnetic Resonance Elastography, Revue Roumanie des Sciences Techniques serie de Mechanique Apliquee, vol. 55, no.1 (2010):3-18. (invited paper; peer reviewed, in English).

16. R.I. Rosca, C.S. Drapaca, Direct and Inverse Problems for the Inversion of a Spherical Shell, Proceedings of the Romanian Academy, Series A, vol.11, no.1 (2010): 33-40. (peer reviewed, in English)

17. K.P. Wilkie, C.S. Drapaca, S. Sivaloganathan, A Theoretical Study of the Effect of Intraventricular Pulsations on the Pathogenesis of Hydrocephalus, Applied Mathematics and Computation, vol.215, no.9 (2010):3181-3191.

18. C.S. Drapaca, A Nonlinear Total Variation-Based Denoising Method with Two Regularization Parameters, IEEE Transactions on Biomedical Engineering, vol.56, no.3 (2009):582-586.

19. C.S. Drapaca, S. Sivaloganathan, G. Tenti, Non-Linear Constitutive Laws in Viscoelasticity, Mathematics and Mechanics of Solids, vol.12, no.5 (2007):475-501.

20. C.S. Drapaca, G. Tenti, K. Rohlf, S. Sivaloganathan, A Quasilinear Viscoelastic Constitutive Equation for the Brain: Application to Hydrocephalus, Journal of Elasticity, vol.85, no.1 (2006):65-83.

21. C. Studholme, C.S. Drapaca, B. Iordanova, V. Cardenas, Deformation Based Mapping of Volume Change from Serial Brain MRI in the Presence of Local Tissue Contrast Change, IEEE Transactions on Medical Imaging, vol.25, no.5 (2006):626-639.

22. C.S. Drapaca, V. Cardenas, C. Studholme, Segmentation of Tissue Boundary Evolution from Brain MR Image Sequences using Multi-phase Level Sets, Computer Vision and Image Understanding, vol.100, issue 3 (2005):312-329.

23. C.S. Drapaca, G. Tenti, S. Sivaloganathan, J.M. Drake, Dynamical Morphology of the Brain’s Ventricular Cavities in Hydrocephalus, Journal of Theoretical Medicine, vol.6, no.3 (2005):151-160.

24. C.S. Drapaca, The Motion of a Viscous Incompressible Fluid with Free Surface through an Elastic Pipe, Annals of the University of Bucharest, Mathematics, vol.XLVI (1997):21-26.

CONFERENCE PAPERS AND ABSTRACTS:

25. C.S. Drapaca, S. Sivaloganathan, Non-local Solutions to Direct and Inverse Problems in Mechanics: A Fractional Calculus Approach, Proceedings of SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2011 Paper No. 102-171 (8 pages; refereed).

26. K. Barber, C.S. Drapaca, A Multiscale Triphasic Biomechanical Model for Tumors Classification, Proceedings of SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2011 Paper No. 34-175 (5 pages; refereed).

27. C.A. Sanchez, C.S. Drapaca, S. Sivaloganathan, E.R. Vrscay, Elastography of Biological Tissue: Direct Inversion Methods that Allow for Local Shear Modulus Variations, Proceedings of the International Conference on Image Analysis and Recognition ICIAR 2010 LNCS 6112 (2010): 195-206. (refereed conference paper).

28. C.S. Drapaca, Modeling the Brain Neuro-Mechanics, Proceedings of the 16th US National Congress of Theoretical and Applied Mechanics 2010 (refereed extended abstract).

29. K.P. Wilkie, C.S. Drapaca, S. Sivaloganathan, A Nonlinear Viscoelastic Fractional Derivative Model of Infant Hydrocephalus, Proceedings of the 16th US National Congress of Theoretical and Applied Mechanics 2010 (refereed extended abstract).

30. A.E. Segall, C. Drapaca, D. Engels, The Inverse Determination of Boundary Conditions using a Least-Squares Approach for Both Linear and Nonlinear Problems, Proceedings of the 16th US National Congress of Theoretical and Applied Mechanics 2010 (refereed extended abstract).

31. C.S. Drapaca, A.J. Palocaren, A Novel Mechanical Model for Tumors’ Classification, Proceedings of SISOM 2010 and Session of the Commission of Acoustics (refereed conference paper).

32. J.Fritz, C.S. Drapaca, A Triphasic Mechano-Electrochemical Model of Brain Neuro-Mechanics: Application to Normal Pressure Hydrocephalus, the Proceedings of the 3rd International Conference in Computational Mechanics and Virtual Engineering COMEC2009, vol.1 (2009):260-265 (refereed conference paper).

33. J. Fritz, C.S. Drapaca, A Study of the Effect of the Pulsatile Ventricular Pressure in the Development of Hydrocephalus, the Proceedings of the 3rd International Conference in Computational Mechanics and Virtual Engineering COMEC2009, vol.1 (2009):254-259 (refereed conference paper).

34. D.L. Andre, B. Shanmugasundaram, C. Drapaca, B. Gluckman, Mechanisms Determining Safety and Performance of Brain Stimulating Electrodes, Proceedings of the 31st Annual International Conference of the IEEE EMBS(2009):689-692 (refereed conference paper).

35. R.I. Rosca, C.S. Drapaca, Direct and Inverse Problems for the Eversion of a Spherical Shell, Proceedings of SISOM 2009 and Session of the Commission of Acoustics (refereed conference paper).

36. D. Engels, A.E. Segall, and C. Drapaca, Inverse Analysis of Thermal States from Transient Histories with Nonlinear Thermophysical Properties, Proceedings of the 2009 ASME Pressure Vessel and Piping Conference, PVP2009-77049 (refereed conference paper).

37. C.S. Drapaca, A New Multi-scale Model for Magnetic Resonance Elastography, Proceedings of SISOM 2008 and Session of the Commission of Acoustics, (2008):66-70 (refereed conference paper).

38. C. Studholme, C.S. Drapaca, V. Cardenas, Intensity Robust Viscous Fluid Deformation Based Morphometry Using Regionally Adapted Mutual Information, Proceedings of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference (2005): 470-473 (refereed conference paper).

39. C. Studholme, C.S. Drapaca, V. Cardenas, M. Weiner, Challenges and Progress Toward Quantitative Deformation Morphometry of Gyral Anatomy, ISBI 2004 (2004):599-602. (refereed conference paper)

40. C.S. Drapaca, V. Cardenas, C. Studholme, Robust Space-Time Extraction of Ventricular Surface Evolution using Multi-Phase Level Sets, Medical Imaging 2004: Image Processing, Proceedings of SPIE, vol.5370 (2004): 538-548 (refereed conference paper).

41. C.S. Drapaca, An Application of the Korteweg-De Vries Equation, Annals of the University of Bucharest, Mathematics - Informatics, Special Issue, Proceedings of the Annual Meeting of the Faculty of Mathematics, November 28-30, 1996, vol.XLVI (1997):121-126 (refereed conference paper).

TECHNICAL REPORTS:

42. D. Aruliah, R.D. Donaldson, C.S. Drapaca, G. Lewis, A. Sanchez, V. Takeva-Volkov, Constitutive Models for Tumor Classification, Proceedings of the OCCAM-Fields-MITACS Biomedical Problem Solving Workshop 2009 (online).

43. C.S. Drapaca, Direct Inversion using Potentials, Mayo Clinic Technical Report, March 2006.

44. C.S. Drapaca, Space-Time Segmentation of Brain Structures using Level Set Methods, UCSF Research Report, May 2003.

OTHER PAPERS:

45. C.S. Drapaca, Brain Neuro-Mechanics, Fields Notes 11:1 (2010): 16-17.

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