Intelligent acoustofluidics
Abstract: Acoustofluidics harnesses sound waves and microfluidics for cell manipulation and liquid handling at the broad interface of engineering, science, and translational medicine. For example, we developed pioneering ‘3D acoustic tweezers’ for single-cell manipulation using surface acoustic waves. This technique uses a pressure gradient to move suspended living cells in a microfluidic environment. Along with this unique contactless, label-free, and highly biocompatible manipulation, this method also offers additional advantages in ease of use, versatility, and portability. To further explore the automation, robustness, and accuracy of our technology, we recently developed ‘intelligent acoustofluidics’ via the fusion of machine learning with acoustofluidics systems. As proof-of-concept applications, we also demonstrated the power of these automatic systems to address challenges in translational medicine.
Bio: Feng Guo is an Assistant Professor of Intelligent Systems Engineering at Indiana University Bloomington. He received his Ph.D. in Engineering Science and Mechanics at the Pennsylvania State University in 2015 and his postdoctoral training at Stanford University School of Medicine. From Fall 2017, Feng started his lab to develop intelligent biomedical devices and systems for fundamental research and emerging translational applications in treating cancer, autoimmune disease, and neural disorder. Feng is the recipient of the 2020 NIH New Innovator Award, Indiana CTSI GLUE Award, Stanford School of Medicine Dean’s Postdoctoral Fellowship, etc.
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