Photo of Ibrahim Ozbolat

Ibrahim Ozbolat

Professor

Affiliation(s):

  • Engineering Science and Mechanics
  • Biomedical Engineering

W313 Millennium Science Complex

ito1@psu.edu

814-863-5819

Personal or Departmental Website

Research Areas:

Emerging Manufacturing Processes for Materials, Tissues, and Devices

 
 

 

Education

  • BS, Industrial Engineering, Middle East Technical University, 2006
  • BS, Mechanical Engineering, Middle East Technical University, 2007
  • Ph D, Industrial and Systems Engineering, University at Buffalo, 2011

Publications

Books

  • Yang Wu, Jerry Fuh and Ibrahim Ozbolat, 2022, 3D Bioprinting in Tissue and Organ Regeneration, Acedemic Press
  • Ibrahim Ozbolat, 2016, 3D Bioprinting: Fundamentals, Principles and Applications, pp. 1-342

Journal Articles

  • R. Xie, V. Pal, Y. Yu, X. Lu, M. Gao, S. Liang, M. Huang, W. Peng and Ibrahim Ozbolat, 2024, "A Comprehensive Review on 3D Tissue Models: Biofabrication Technologies and Preclinical Applications", Biomaterials, 304, pp. 122408
  • M. A. Alioglu, Y. O. Yilmaz, E. M. Gerhard, V. Pal, D. Gupta, H. Rizvi and Ibrahim Ozbolat, 2024, "A Versatile Photocrosslinkable Silicone Composite for 3D Printing Applications", Advanced Material Technologies, 9, pp. 2301858
  • Y. Kang, M. Yeo, I. D. Derman, D. J. Ravnic, Y. P. Singh, M. A. Alioglu, Y. Wu, J. Makkar Peng, R. R. Driskell and Ibrahim Ozbolat, 2024, "Bioprinting of Human Adipose-derived Stem cells and Extra-cellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation during Full-thickness Craniomaxillofacial Skin Reconstruction", Bioactive Materials, 33, pp. 114-128
  • Y. Wu, X. Yang, D. Gupta, M. A. Alioglu, M. Qin, V. Ozbolat, Y. Li and Ibrahim Ozbolat, 2024, "Dissecting the Interplay Mechanism among Process Parameters towards the Biofabrication of High Quality Shapes in Embedded Bioprinting", Advanced Functional Materials, pp. 2313088
  • M. Alioglu, Y. O. Yilmaz, Y. P. Singh, M. Nagamine, N. Celik, M. K. Kim, V. Pal, D. Gupta and Ibrahim Ozbolat, 2024, "Nested biofabrication: Matryoshka-inspired Intra-embedded Bioprinting", Small Methods, pp. 2301325
  • N. Celik, S. Koduru, D. Ravnic, Ibrahim Ozbolat and D. Hayes, 2024, "Post-transcriptional Modification to Modulate Progenitor Differentiation on Heterotypic Spheroids", Tissue Engineering Part A
  • Ibrahim Ozbolat, 2024, "Advancing the field of 3D bioprinting: an interview with Ibrahim T. Ozbolat", Journal of 3D Printing in Medicine, 7, (3), pp. 3DP012
  • M. Yeo, A. Sarkar, Y. P. Singh, I. D. Derman, P. Datta and Ibrahim Ozbolat, 2024, "Synergistic coupling between 3D bioprinting and vascularization strategies", Biofabrication, 16, pp. 012003
  • C. Tuftee, E. Alsberg, Ibrahim Ozbolat and M. Rizwan, 2024, "Emerging granular hydrogel bioinks to improve biological function in bioprinted constructs", Trends in Biotechnology
  • D. Banerjee, M. Ivanova, N. Celik, M. H. Kim, I. D. Derman, R. P. Limgala, Ibrahim Ozbolat and O. Goker-Alpan, 2023, "Biofabrication of an in-vitro bone model for Gaucher disease", Biofabrication, 15, (4), pp. 045023
  • I. D. Derman, M. Yeo, D. C. Castaneda, M. Callender, M. Horvath, Z. Mo, R. Xiong, E. Fleming, P. Chen, M. Peeples, K. Palucka, J. Oh and Ibrahim Ozbolat, 2023, "High-Throughput Bioprinting of the Nasal Epithelium using Patient-derived Nasal Epithelial Cells", Biofabrication, 15, (4), pp. 044103
  • D. Gupta, B. Chickhkov, Z. J. Vereb and Ibrahim Ozbolat, 2023, "Editorial: Innovative 3D technologies in cancer immunity research and therapy", Frontiers in Immunology, 14, pp. 1235483
  • V. Pal, Y. P. Singh, D. Gupta, M. A. Alioglu, M. Nagamine, M. H. Kim and Ibrahim Ozbolat, 2023, "High-throughput microgel biofabrication via air-assisted co-axial jetting for cell encapsulation, 3D bioprinting and scaffolding applications", Biofabrication, 15, (3), pp. 035001
  • M. Alioglu, Y. P. Singh, M. Nagamine, S. H. Rizvi, V. Pal, E. M. Gerhard, S. Saini, M. H. Kim and Ibrahim Ozbolat, 2023, "3D Embedded Printing of Microfluidic Devices using a Functional Silicone Composite Support Bath", Additive Manufacturing, 70, pp. 103566
  • Pallab Datta, Laura Cabrera and Ibrahim Ozbolat, 2023, "Ethical Challenges with 3D Bioprinted Tissues and Organs", Trends in Biotechnology, 41, (1), pp. 6-9
  • Saad Asim, Tanveer Tabish, Shweta Saini, Usman Liaqat, Ibrahim Ozbolat and Muhammad Rizwan, 2023, "Advances in Gelatin Bioinks to Optimize Bioprinted Cell Functions", Advanced Healthcare Materials, pp. 2203148
  • K.K K Moncal, Miji Yeo, Nazmiye Celik , T Acti, E Rizk, H Wee, G Lewis, A Salem and Ibrahim Ozbolat, 2023, "Comparison of In-Situ versus Ex-Situ Delivery of Polyethylenimine-BMP-2 polyplexes for Rat Calvarial Defect Repair via Intraoperative Bioprinting", Biofabrication, 15, (1), pp. 015011
  • Irem Deniz Derman, Yogendra Singh, Shweta Saini, Momoka Nagamine, Dishary Banerjee and Ibrahim Ozbolat, 2023, "Bioengineering and Clinical Translation of Human Lung and its Components", Advanced Biology, pp. 2200267
  • C. McLaughlin, P. Datta, Y. P. Singh, A. Lo, S. Horchler, I. Elcheva, Ibrahim Ozbolat, D. Ravnic and S. Koduru, 2022, "Mesenchymal Stem Cell Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Application", Cells, 11, (21), pp. 3366
  • D. Banerjee, Y. P. Singh, P. Datta, V. Ozbolat, A. O'Donnell, M. Yeo and Ibrahim Ozbolat, 2022, "Strategies for 3D Bioprinting of Tissue Spheroids: A Comprehensive Review", Biomaterials, 291, pp. 121881
  • M. Dey, M. H. Kim, M. Dogan, M. Nagamine, L. Kozhaya, N. Celik, D. Unutmaz and Ibrahim Ozbolat, 2022, "Chemotherapeutics and CAR-T cell-based immunotherapeutics screening on a 3D bioprinted vascularized breast tumor model", Advanced Functional Materials, 32, (52), pp. 202203966
  • M. Dey, M. H. Kim, M. Nagamine, E. Korhan, L. Kozhaya, M. Dogan, D. Unutmaz and Ibrahim Ozbolat, 2022, "Biofabrication of 3D breast cancer models for dissecting the cytotoxic response of human T cells expressing engineered MAIT cell receptors", Biofabrication, 14, (4), pp. 044105
  • K Moncal, Seda Tigli, K Godzik, T Acri, D Heo, E Rizk, H Wee, G Lewis, A Salem and Ibrahim Ozbolat, 2022, "Controlled Co-delivery of pPDGF-B and pBMP-2 from intraoperatively bioprinted bone constructs improves the repair of calvarial defects in rats", Biomaterials, 281, pp. 121333
  • Karwowski-Hospodiuk M, S.M.Q Bokhari, K Chi, K.K Moncal, V Ozbolat, Ibrahim Ozbolat and J Catchmark, 2022, "Dual-charge bacterial cellulose as a potential 3D printable material for soft tissue engineering", Composites Part B: Engineering, 231, pp. 109598
  • Myoung Hwan Kim, Dishary Banerjee, Nazmiye Celik and Ibrahim Ozbolat, 2022, "Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels", Biofabrication, 14, pp. 024103
  • N. Celik, M. H. Kim, M. Yeo, F. Kamal, D. Hayes and Ibrahim Ozbolat, 2022, "miRNA induced 3D bioprinted-heterotypic osteochondral interface", Biofabrication, 14, (4), pp. 044104
  • T. S. Mohan, P. Datta, S. Nesaei, V. Ozbolat and Ibrahim Ozbolat, 2022, "3D Coaxial bioprinting: Process mechanisms, bioinks and applications", Progress in Biomedical Engineering, 4, pp. 022003
  • Anisha Kabir, Pallab Datta, Julia Oh, Adam Williams, Veli Ozbolat, Derya Unutmaz and Ibrahim Ozbolat, 2021, "3D Bioprinting for fabrication of tissue models of COVID-19 infection", Essays in Biochemistry
  • Ibrahim Ozbolat, Roghayeh Khoeini, Hamed Nosrati, Abolfazl Akbarzadeh, Aziz Eftekhari, Taras Kavetskyy, Rovshan Khalilov, Elham Ahmadian, Aygun Nasibova, Pallab Datta, Leila Roshangar, Dante C. Deluca, Soodabeh Davaran and Magali Cucchiarini, 2021, "Natural and Synthetic Bioinks for 3D Bioprinting", Advanced NanoBiomed Research, pp. 2000097
  • N Celik, Myoung Hwan Kim, D Hayes and Ibrahim Ozbolat, 2021, "miRNA induced co-differentiation and cross-talk of adipose tissue-derived progenitor cells for 3D heterotypic pre-vascularized bone formation", Biofabrication, 13, (4), pp. 044107
  • Tarun Agarwal, Dishary Banerjee, Rocktotpal Konwarh, Timothy Esworthy, Jyoti Kumari, Valentina Onesto, Prativa Das, Bae Hoon Lee, Frank ADTG Wagener, Pooyan Makvandi, Virgilio Mattoli, Sudip Kumar Ghosh, Tapas Kumar Maiti, Lijie Grace Zhang and Ibrahim Ozbolat, 2021, "Recent advances in bioprinting technologies for engineering hepatic tissue", Materials Science and Engineering: C, 123, pp. 112013
  • Madhuri Dey, Bugra Ayan, Marina Yurieva, Derya Unutmaz and Ibrahim Ozbolat, 2021, "Studying Tumor Angiogenesis and Cancer Invasion in a Three-Dimensional Vascularized Breast Cancer Micro-Environment", Advanced Biology, 5, (7), pp. 2100090
  • Kazim K Moncal, Hemanth Gudapati, Kevin P Godzik, Dong N Heo, Youngnam Kang, Elias Rizk, Dino J Ravnic, Hwabok Wee, David F Pepley, , Veli Ozbolat, Gregory S Lewis, Jason Z Moore, Ryan R Driskell, Thomas D Samson and Ibrahim Ozbolat, 2021, "Intra-Operative Bioprinting of Hard, Soft, and Hard/Soft Composite Tissues for Craniomaxillofacial Reconstruction", Advanced Functional Materials, 31, (29), pp. 2010858
  • Yang Wu, Patrick Kennedy, Nicholas Bonazza, Yin Yu, Aman Dhawan and Ibrahim Ozbolat, 2021, "Three-dimensional bioprinting of articular cartilage: A systematic review", Cartilage, 12, (1), pp. 76-92
  • George A Kuchel, Alan Landay, Jenna M Bartley, Dishary Banerjee, Geneva Hargis, Laura Haynes, Ali Keshavarzian, Chia-Ling Kuo, Oh Sung Kwon, Sheng Li, Shuzhao Li, Julia Oh, Ibrahim Ozbolat, Duygu Ucar, Ming Xu, Xudong Yao and Derya Unutmaz, 2021, "Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19", Frontiers in Aging, 2, pp. 23
  • DongNyoung Heo, Bugra Ayan, Madhuri Dey, Dishary Banerjee, Hwabok Wee, Gregory S Lewis and Ibrahim Ozbolat, 2021, "Aspiration-assisted bioprinting of co-cultured osteogenic spheroids for bone tissue engineering", Biofabrication, 13, (1), pp. 015013
  • Kui Zhou, Madhuri J Dey, Bugra Ayan, Zhifeng Zhang, Veli Ozbolat, Myoung Hwan Kim, Vladimir Khristov and Ibrahim Ozbolat, 2021, "Fabrication of PDMS microfluidic devices using nanoclay-reinforced Pluronic F-127 as a sacrificial ink", Biomedical Materials, 16, (4), pp. 045005
  • Srinivas V Koduru, Ashley N Leberfinger, Ibrahim Ozbolat and Dino J Ravnic, 2021, "Navigating the Genomic Landscape of Human Adipose Stem Cell-Derived ß-Cells", Stem Cells and Development, 30, (23), pp. 1153-1170
  • Nazmiye Celik, Myoung Hwan Kim, Daniel J Hayes and Ibrahim T Ozbolat, 2021, "miRNA induced co-differentiation and cross-talk of adipose tissue-derived progenitor cells for 3D heterotypic pre-vascularized bone formation", Biofabrication, 13, (4), pp. 044107
  • R. Khoeini, H. Nosrati, A. Akbarzadeh, A. Eftekhari, T. Kavetskyy, R. Khalilov, E. Ahmadian, A. Nasibova, P. Datta, L. Roshangar, D. Deluca, S. Davaran, M. Cucchiarini and Ibrahim Ozbolat, 2021, "Natural and Synthetic Bioinks for 3D Bioprinting", Advanced NanoBiomed Research, 1, (8), pp. 2000097
  • Bugra Ayan, Dong Nyoung Heo, Zhifeng Zhang, Madhuri Dey, Adomas Povilianskas, Corina Drapaca and Ibrahim Ozbolat, 2020, "Aspiration-assisted bioprinting for precise positioning of biologics", Science Advances, 6, (10), pp. eaaw5111
  • Dong Nyoung Heo, Mecit Altan Alioglu, Yang Wu, Veli Ozbolat, Bugra Ayan, Madhuri Dey, Youngnam Kang and Ibrahim Ozbolat, 2020, "3D Bioprinting of Carbohydrazide-Modified Gelatin into Microparticle-Suspended Oxidized Alginate for the Fabrication of Complex-Shaped Tissue Constructs", ACS Applied Materials & Interfaces, 12, (18), pp. 20295-20306
  • Pallab Datta, Madhuri Dey, Zaman Ataie, Derya Unutmaz and Ibrahim Ozbolat, 2020, "3D bioprinting for reconstituting the cancer microenvironment", npj Precision Oncology, 4, (1), pp. 1-13
  • Bugra Ayan, Yang Wu, Vengadeshprabhu Karuppagounder, Fadia Kamal and Ibrahim Ozbolat, 2020, "Aspiration-assisted bioprinting of the osteochondral interface", Scientific Reports, 10, (1), pp. 1-12
  • Madhuri Dey and Ibrahim Ozbolat, 2020, "Editorial: 3D bioprinting of cells, tissues and organs", Scientific Reports, 10, (1), pp. 1-3
  • Youngnam Kang, Pallab Datta, Shanmughapriya Santhanam and Ibrahim Ozbolat, 2020, "3D Bioprinting of Tumor Models for Cancer Research", ACS Applied Bio Materials, 3, (9), pp. 5552-5573
  • Hemanth Gudapati, Daniele Parisi, Ralph H Colby and Ibrahim Ozbolat, 2020, "Rheological investigation of collagen, fibrinogen, and thrombin solutions for drop-on-demand 3D bioprinting", Soft Matter, 16, (46), pp. 10506-10517
  • Hemanth Gudapati and Ibrahim Ozbolat, 2020, "The role of concentration on drop formation and breakup of collagen, fibrinogen, and thrombin solutions during inkjet bioprinting", Langmuir, 36, (50), pp. 15373-15385
  • Yang Wu, Dino Ravnic and Ibrahim Ozbolat, 2020, "Intraoperative bioprinting: repairing tissues and organs in a surgical setting", Trends in biotechnology, 38, (6), pp. 594-605
  • Bugra Ayan, Nazmiye Celik, Zhifeng Zhang, Kui Zhou, Myoung Hwan Kim, Dishary Banerjee, Yang Wu, Francesco Costanzo and Ibrahim Ozbolat, 2020, "Aspiration-assisted freeform bioprinting of pre-fabricated tissue spheroids in a yield-stress gel", Communications physics, 3, (1), pp. 1-14
  • Yang Wu, Bugra Ayan, Kazim Moncal, Youngnam Kang, Aman Dhawan, Srinivas Koduru, Dino Ravnic, Fadia Kamal and Ibrahim Ozbolat, 2020, "Hybrid Bioprinting of Zonally Stratified Human Articular Cartilage Using Scaffold-Free Tissue Strands as Building Blocks", Advanced Healthcare Materials, 9, (22), pp. 2001657
  • Wei Sun, Binil Starly, Andrew C Daly, Jason A Burdick, Jürgen Groll, Gregor Skeldon, Wenmiao Shu, Yasuyuki Sakai, Marie Shinohara, Masaki Nishikawa, Jinah Jang, Dong-Woo Cho, Minghao Nie, Shoji Takeuchi, Serge Ostrovidov, Ali Khademhosseini, Roger D Kamm, Vladimir Mironov, Lorenzo Moroni and Ibrahim Ozbolat, 2020, "The Bioprinting roadmap", Biofabrication, 12, (2), pp. 022002
  • Kazim K. Moncal, Veli Ozbolat, Pallab Datta, Dong N. Heo and Ibrahim Ozbolat, 2019, "Thermally-controlled extrusion-based bioprinting of collagen", Journal of Materials Science: Materials in Medicine, 30, (55), pp. 1-14
  • Veli Ozbolat, Madhuri Dey, Bugra Ayan and Ibrahim Ozbolat, 2019, "Extrusion-based printing of sacrificial Carbopol ink for fabrication of microfluidic devices", Biofabrication, 11, (3), pp. 034101
  • Srinivas Koduru, Ashley N. Leberfinger, Denis Pasic, Anoosha Forghani, Shane Lince, Daniel Hayes, Ibrahim Ozbolat and Dino J Ravnic, 2019, "Cellular Based Strategies for Microvascular Engineering", Stem Cell Reviews and Reports, 15, (2), pp. 218-240
  • Aman Dhawan, Patrick Merrill Kennedy, Elias B Rizk and Ibrahim Ozbolat, 2019, "Three-dimensional bioprinting for bone and cartilage restoration in orthopaedic surgery", Journal of the American Academy of Orthopaedic Surgeons, 27, (5), pp. E215-E226
  • Songul Ulag, Cevriye Kalkandelen, Faik Nuzhet Oktar, Muhammet Uzun, Yesim Muge Sahin, Betul Karademir, Sema Arslan, Ibrahim Ozbolat, Mahir Mahirogullari and Oguzhan Gunduz, 2019, "3D Printing Artificial Blood Vessel Constructs Using PCL/Chitosan/Hydrogel Biocomposites", ChemistrySelect, 4, (8), pp. 2387-2391
  • Dong Nyoung Heo, Monika Hospodiuk and Ibrahim Ozbolat, 2019, "Synergistic interplay between human MSCs and HUVECs in 3D spheroids laden in collagen/fibrin hydrogels for bone tissue engineering", Acta Biomaterialia, 95, pp. 348-356
  • A Dotta, A Wali, Yang Wu, A Ponnone, L K Reddy, S Ozdemir, Ibrahim Ozbolat and Saptarshi Das, 2019, "Biological One-Way Function for Secure Key Generation", Advanced Theory and Simulations, 2, (2), pp. 1800154
  • A Wali, A Dotta, Yang Wu, A Ponnone, L K Reddy, S Ozdemir, Ibrahim Ozbolat and Saptarshi Das, 2019, "Biological - Physically Unclonable functon (Bio-PUF)", Communications Physics, 2, (1), pp. 39
  • Kazim Moncal, R.S.D. Aydin, M. Abu-Laban, D. N. Heo, Elias Rizk, Scott M. Tucker, G. S. Lewis, D. Hayes and Ibrahim Ozbolat, 2019, "Collagen-infilled 3D printed scaffolds loaded with miR-148b-transfected bone marrow stem cells improve calvarial bone regeneration in rats", Materials Science and Engineering: C, 105, pp. 110128
  • Yang Wu, Monika Hospodiuk, Weijie Peng, Hemanth Gudapati, Thomas Neuberger, Srinivas Koduru, Dino J. Ravnic and Ibrahim Ozbolat, 2019, "Porous tissue strands: avascular building blocks for scalable tissue fabrication", Biofabrication, 11, (1), pp. 015009
  • Ashley N. Leberfinger, Shantanab Dinda, Yang Wu, Srinivas Koduru, Veli Ozbolat, Dino J Ravnic and Ibrahim Ozbolat, 2019, "Bioprinting functional tissues", Acta Biomaterialia, 95, pp. 32-49
  • Kazim K. Moncal, Dong N. Heo, Kevin P. Godzik, Donna M. Sosnoski, Oliver D. Mrowczynski, Elias B Rizk, Veli Ozbolat, Scott M. Tucker, Ethan M. Gerhard, Madhuri Dey, Gregory Stephen Lewis, Jian Yang and Ibrahim Ozbolat, 2018, "3D printing of poly(?-caprolactone)/poly(D,L-lactide-co-glycolide)/hydroxyapatite composite constructs for bone tissue engineering", Journal of Materials Research, 33, (14), pp. 1972-1986
  • P Sasmal, P Datta, Yang Wu and Ibrahim Ozbolat, 2018, "3D Bioprinting for Modeling of Vasculature", MicroPyhsiological Systems, 2, (9), pp. 1-17
  • Yang Wu, Patrick Kennedy, Nicholas Bonazza, Yin Yu, Aman Dhawan and Ibrahim Ozbolat, 2018, "Three-Dimensional Bioprinting of Articular Cartilage: A Systematic Review", Cartilage
  • Veli Ozbolat, Madhuri Dey, Bugra Ayan, Adomas Povidianskas, Melik C Demirel and Ibrahim Ozbolat, 2018, "3D Printing of PDMS Improves Its Mechanical and Cell Adhesion Properties", ACS Biomaterials Science & Engineering, 4, (2), pp. 682-693
  • Mert Vural, Abdon Pena-Francesch, Joan Bars-Pomes, Huihun Jung, Hemanth Gudapati, Christine B. Hatter, Benjamin D Allen, Babak Anasori, Ibrahim Ozbolat, Yury Gogotsi and Melik C Demirel, 2018, "Inkjet Printing of Self-Assembled 2D Titanium Carbide and Protein Electrodes for Stimuli-Responsive Electromagnetic Shielding", Advanced Functional Materials, 28, (32), pp. 1801972
  • Monika Hospodiuk, Madhuri Dey, Bugra Ayan, Donna Sosnoski, Kazim K. Moncal, Yang Wu and Ibrahim Ozbolat, 2018, "Sprouting angiogenesis in engineered pseudo islets", Biofabrication, 10, (3), pp. 035003
  • Ashley N. Leberfinger, Monika Hospodiuk, Abdon Pena-Francesch, Bugra Ayan, Veli Ozbolat, Srinivas V. Koduru, Ibrahim Ozbolat, Melik C Demirel and Dino J. Ravnic, 2018, "Squid Ring Teeth-coated Mesh Improves Abdominal Wall Repair", Plastic and Reconstructive Surgery-Global Open, 6, (8), pp. e1881
  • Aishwarya Satpathy, Pallab Datta, Yang Wu, Bugra Ayan, Ertugrul Bayram and Ibrahim Ozbolat, 2018, "Developments with 3D bioprinting for novel drug discovery", Expert Opinion on Drug Discovery, 13, (12), pp. 1115-1129
  • Pallab Datta, Ananya Barui, Yang Wu, Veli Ozbolat, Kazim K. Moncal and Ibrahim Ozbolat, 2018, "Essential steps in bioprinting: From pre- to post-bioprinting", Biotechnology Advances, 36, (5), pp. 1481-1504
  • Monika Hospodiuk, Madhuri Dey, Donna Sosnoski and Ibrahim Ozbolat, 2017, "The bioink: A comprehensive review on bioprintable materials", Biotechnology Advances, 35, (2), pp. 217-239
  • Pallab Datta, Aman Dhawan, Yin Yu, Dan Hayes, Hemanth Gudapati and Ibrahim Ozbolat, 2017, "Bioprinting of osteochondral tissues: A perspective on current gaps and future trends", International Journal of Bioprinting, 3, (2), pp. 109-120
  • Anh-Vu Do, Adil Akkouch, Brian Green, Ibrahim Ozbolat, Amer Debabneh, Sean Geary and Aliasger K. Salem, 2017, "Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes", Annals of Biomedical Engineering, 45, (1), pp. 297-305
  • Weijie Peng, Pallab Datta, Bugra Ayan, Veli Ozbolat, Donna Sosnoski and Ibrahim Ozbolat, 2017, "3D bioprinting for drug discovery and development in pharmaceutics", Acta Biomaterialia, 57, pp. 26-46
  • Dino J. Ravnic, Ashley N. Leberfinger and Ibrahim Ozbolat, 2017, "Bioprinting and Cellular Therapies for Type 1 Diabetes", Trends in Biotechnology, 35, (11), pp. 1025-1034
  • Pallab Datta, Bugra Ayan and Ibrahim Ozbolat, 2017, "Bioprinting for vascular and vascularized tissue biofabrication", Acta Biomaterialia, 51, pp. 1-20
  • Pallab Datta, Veli Ozbolat, Bugra Ayan, Aman Dhawan and Ibrahim Ozbolat, 2017, "Bone Tissue Bioprinting for Craniofacial Reconstruction", Biotechnology and Bioengineering, 114, (11), pp. 2424-2431
  • Ashley N. Leberfinger, Dino J. Ravnic, Aman Dhawan and Ibrahim Ozbolat, 2017, "Concise Review: Bioprinting of Stem Cells for Transplantable Tissue Fabrication", Stem Cells Translational Medicine, 6, (10), pp. 1940-1948
  • Ethan Michael Gerhard, Wei Wang, Caiyan Li, Jinshan Guo, Ibrahim Ozbolat, Kevin Michael Rahn, April Dawn Armstrong, Jingfen Xia, Guoying Qian and Jian Yang, 2017, "Design strategies and applications of nacre-based biomaterials", Acta Biomaterialia, 54, pp. 21-34
  • Ibrahim Ozbolat, Kaizim K. Moncal and Hemanth Gudapati, 2017, "Evaluation of bioprinter technologies", Additive Manufacturing, 13, pp. 179-200
  • Dino J. Ravnic, Ashley N. Leberfinger, Srinivas V. Koduru, Monika Hospodiuk, Kazim K. Moncal, Pallab Datta, Madhuri Dey, Elias Rizk and Ibrahim Ozbolat, 2017, "Transplantation of Bioprinted Tissues and Organs Technical and Clinical Challenges and Future Perspectives", Annals of Surgery, 266, (1), pp. 48-58
  • Stephanie Knowlton, Ashwini Joshi, Bekir Yenilmez, Ibrahim Ozbolat, Chee Kai Chua, Ali Khademhosseini and Savas Tasoglu, 2016, "Advancing cancer research using bioprinting for tumor-on-a-chip platforms", International Journal of Bioprinting, 2, (2), pp. 3-8
  • Martin Heller, Heide Katharina Bauer, Elisabeth Goetze, Matthias Gielisch, Ibrahim Ozbolat, Kazim K. Moncal, Elias B Rizk, Hermann Seitz, Michael Gelinsky, Heinz C. Schröder, Xiaohong H. Wang, Werner E. Werner and Bilal Al-Nawas, 2016, "Materials and scaffolds in medical 3D printing and bioprinting in the context of bone regeneration", International Journal of Computerized Dentistry, 19, (4), pp. 301-321
  • Ibrahim Ozbolat and Hemanth Gudapati, 2016, "A review on design for bioprinting", Bioprinting, 3, pp. 1-14
  • Yin Yu, Kazim K. Moncal, Jianqiang Li, Weijie Peng, Iris Rivero, James A. Martin and Ibrahim Ozbolat, 2016, "Three-dimensional bioprinting using self-assembling scalable scaffold-free "tissue strands" as a new bioink", Scientific Reports, 6, pp. 28714
  • Hemanth Gudapati, Madhuri Dey and Ibrahim Ozbolat, 2016, "A comprehensive review on droplet-based bioprinting: Past, present and future", Biomaterials, 102, pp. 20-42
  • Ibrahim Ozbolat, Weijie Peng and Veli Ozbolat, 2016, "Application areas of 3D bioprinting", Drug Discovery Today, 21, (8), pp. 1257-1271
  • Weijie Peng, Derya Unutmaz and Ibrahim Ozbolat, 2016, "Bioprinting towards Physiologically Relevant Tissue Models for Pharmaceutics", Trends in Biotechnology, 34, (9), pp. 722-732
  • Ibrahim Ozbolat and Monika Hospodiuk, 2016, "Current advances and future perspectives in extrusion-based bioprinting", Biomaterials, 76, pp. 321-343
  • Ibrahim Ozbolat, 2015, "Editorial: Special Issue on Three-Dimensional Bioprinting", Journal of Nanotechnology in Engineering and Medicine, 6, (2), pp. 020301
  • Ibrahim Ozbolat, 2015, "Scaffold-Based or Scaffold-Free Bioprinting: Competing or Complementing Approaches?", Journal of Nanotechnology in Engineering and Medicine, 6, (2), pp. 024701
  • Yahui Zhang, Yin Yu, Adil Akkouch, Amer Dababneh, Farzaneh Dolati and Ibrahim Ozbolat, 2015, "In vitro study of directly bioprinted perfusable vasculature conduits", Biomaterials Science, 3, (1), pp. 134-143
  • Adil Akkouch, Yin Yu and Ibrahim Ozbolat, 2015, "Microfabrication of scaffold-free tissue strands for three-dimensional tissue engineering", Biofabrication, 7, (3), pp. 031002
  • Amer Dababneh and Ibrahim Ozbolat, 2015, "Predictive reliability and lifetime methodologies for circuit boards", Journal of Manufacturing Systems, 37, pp. 141-148
  • Ninggang Shen, Hongtao Ding, Robert Bowers, Yin Yu, Chelsey N. Pence, Ibrahim Ozbolat and Clark M. Stanford, 2015, "Surface Micropatterning of Pure Titanium for Biomedical Applications Via High Energy Pulse Laser Peening", Journal of Micro and Nano-manufacturing, 3, (1), pp. 011005
  • Ibrahim Ozbolat, 2015, "Bioprinting scale-up tissue and organ constructs for transplantation", Trends in Biotechnology, 33, (7), pp. 395-400
  • Amer B. Dababneh and Ibrahim Ozbolat, 2014, "Bioprinting Technology: A Current State-of-the-Art Review", Journal of Manufacturing Science and Engineering, 136, (6), pp. 061013
  • Amer B. Dababneh, Ben Goerdt, Timothy Marler and Ibrahim Ozbolat, 2014, "A Virtual Prognostic Tool for Nuclear Power Electronics Reliability", Computer-Aided Design and Applications, 11, (2), pp. 228-238
  • Yin Yu, Yahui Zhang and Ibrahim Ozbolat, 2014, "A Hybrid Bioprinting Approach for Scale-Up Tissue Fabrication", Journal of Manufacturing Science and Engineering, 136, (6), pp. 061016
  • Ibrahim Ozbolat, Khoda and A. K. M. B., 2014, "Design of a New Parametric Path Plan for Additive Manufacturing of Hollow Porous Structures With Functionally Graded Materials", Journal of Computing and Information Science in Engineering, 14, (4), pp. 041005
  • Ibrahim Ozbolat, Howard Chen and Yin Yu, 2014, "Development of 'Multi-arm Bioprinter' for hybrid biofabrication of tissue engineering constructs", Robotics and Computer-Integrated Manufacturing, 30, (3), pp. 295-304
  • Yahui Zhang, Yin Yu, Farzaneh Dolati and Ibrahim Ozbolat, 2014, "Effect of multiwall carbon nanotube reinforcement on coaxially extruded cellular vascular conduits", Materials Science and Engineering: C, 39, pp. 126-133
  • Farzaneh Dolati, Yin Yu, Yahui Zhang, De Jesus, Aribet M., Edward A. Sander and Ibrahim Ozbolat, 2014, "In vitro evaluation of carbon-nanotube-reinforced bioprintable vascular conduits", Nanotechnology, 25, (14), pp. 145101
  • Kuntal Samanta, Ibrahim Ozbolat and Bahattin Koc, 2014, "Optimized normal and distance matching for heterogeneous object modeling", Computers & Industrial Engineering, 69, pp. 1-11
  • Yahui Zhang, Yin Yu and Ibrahim Ozbolat, 2013, "Direct bioprinting of vessel-like tubular microfluidic channels", Journal of Nanotechnology in Engineering and Medicine, 4, (2), pp. 1-7
  • A. K.M. Khoda, Ibrahim Ozbolat and Bahattin Koc, 2013, "Modeling of variational gradient porous architecture with multidirectional filament deposition in 3D scaffolds", Computer-Aided Design and Applications, 10, (3), pp. 445-459
  • Ibrahim Ozbolat and Yin Yu, 2013, "Bioprinting Toward Organ Fabrication: Challenges and Future Trends", IEEE Transactions on Biomedical Engineering, 60, (3), pp. 691-699
  • Yahui Zhang, Yin Yu, Howard Chen and Ibrahim Ozbolat, 2013, "Characterization of printable cellular micro-fluidic channels for tissue engineering", Biofabrication, 5, (2), pp. 024004
  • Ibrahim Ozbolat, Michelle Marchany, Gardella, Joseph A., Jr. and Bahattin Koc, 2013, "Computer-Aided 4D Modeling of Hydrolytic Degradation in Micropatterned Bioresorbable Membranes", Journal of Medical Devices, 7, (2), pp. 021004
  • Khoda, A. K. M., Ibrahim Ozbolat and Bahattin Koc, 2013, "Designing heterogeneous porous tissue scaffolds for additive manufacturing processes", Computer-Aided Design, 45, (12), pp. 1507-1523
  • Yin Yu, Yahui Zhang, James A. Martin and Ibrahim Ozbolat, 2013, "Evaluation of Cell Viability and Functionality in Vessel-like Bioprintable Cell-Laden Tubular Channels", Journal of Biomechanical Engineering, 135, (9), pp. 021001
  • Ibrahim Ozbolat, Amer Dababneh, Omer Elgaali, Yahui Zhang, Timothy Marler and Steven Turek, 2012, "A model based enterprise approach in electronics manufacturing", Computer-Aided Design and Applications, 9, (6), pp. 847-856
  • Ibrahim Ozbolat, A. K.M.B. Khoda, Michelle Marchany, Joseph A. Gardella and Bahattin Koc, 2012, "Hybrid tissue scaffolds for controlled release applications: A study on design and fabrication of hybrid and heterogeneous tissue scaffolds for controlled release applications is presented in this paper", Virtual and Physical Prototyping, 7, (1), pp. 37-47
  • Ibrahim Ozbolat and Bahattin Koc, 2012, "3D hybrid wound devices for spatiotemporally controlled release kinetics", Computer Methods and Programs in Biomedicine, 108, (3), pp. 922-931
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "A continuous multi-material toolpath planning for tissue scaffolds with hollowed features", Computer-Aided Design and Applications, 8, (2), pp. 237-247
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "Multi-function based modeling of 3D heterogeneous wound scaffolds for improved wound healing", Computer-Aided Design and Applications, 8, (1), pp. 43-57
  • A. K Khoda, Ibrahim Ozbolat and Bahattin Koc, 2011, "Engineered tissue scaffolds with variational porous architecture", Journal of Biomechanical Engineering, 133, (1), pp. 011001
  • Khoda, A. K. M., Ibrahim Ozbolat and Bahattin Koc, 2011, "A functionally gradient variational porosity architecture for hollowed scaffolds fabrication", Biofabrication, 3, (3), pp. 034106
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "Multi-directional blending for heterogeneous objects", Computer-Aided Design, 43, (8), pp. 863-875
  • Ibrahim Ozbolat and Bahattin Koc, 2010, "Modeling of Spatially Controlled Biomolecules in Three-Dimensional Porous Alginate Structures", Journal of Medical Devices, 4, (4), pp. 041003
  • Ibrahim Ozbolat, Michelle Marchany, Joseph A. Gardella, Frank V. Bright, Alex N. Cartwright, Robert Hard, Wesley L. Hicks and Bahattin Koc, 2009, "Feature-based design of bio-degradable micro-patterned structures", Computer-Aided Design and Applications, 6, (5), pp. 661-671

Conference Proceedings

  • Amer B. Dababneh and Ibrahim Ozbolat, 2014, "A virtual reliability tool for circuit boards", pp. 72-77
  • Farzaneh Dolati, Yin Yu, Yahui Zhang and Ibrahim Ozbolat, 2014, "Carbon-nanotube reinforced vascular conduits", pp. 1-10
  • Yahui Zhang, Farzaneh Dolati, Yin Yu and Ibrahim Ozbolat, 2014, "Effect of carbon nanotube reinforcement on coaxially extruded vascular conduits", 42, pp. 178-185
  • Ninggang Shen, Chelsey N. Pence, Robert Bowers, Yin Yu, Hongtao Ding, Clark M. Stanford and Ibrahim Ozbolat, 2014, "Surface micro-scale patterning for biomedical implant material of pure titanium via high energy pulse laser peening", 2, pp. 1-7
  • Yin Yu and Ibrahim Ozbolat, 2014, "Tissue strands as "bioink" for scale-up organ printing", pp. 1428-1431
  • J. Xu, Tim Marler and Ibrahim Ozbolat, 2014, "Reverse Engineering of Nuclear Electronics"
  • Yahui Zhang, Yin Yu and Ibrahim Ozbolat, 2013, "Characterization of printable micro-fluidic channels for organ printing", 1
  • Yahui Zhang and Ibrahim Ozbolat, 2013, "Characterization of vessel-like printable cellular microfluidic channel", pp. 2291-2298
  • A. K.M. Khoda, Ibrahim Ozbolat and Bahattin Koc, 2013, "Functionally gradient tissue scaffold design and deposition path planning for bio-additive processes", pp. 2253-2262
  • Benjamin B. Goerdt, Amer Dababneh, Timothy Marler, Ibrahim Ozbolat, Benjamin Weintraub and Ross Johnson, 2013, "Integration of a reliability model within a virtual analysis system for printed circuit boards", 11
  • A. K.M.Bashirul Khoda, Ibrahim Ozbolat and Bahattin Koc, 2013, "Spatially multi-functional porous tissue scaffold", 59, pp. 174-182
  • Ibrahim Ozbolat, 2013, "3D functional organ printing: Promises and future challenges", pp. 2220-2226
  • Howard Chen and Ibrahim Ozbolat, 2013, "A multi-material bioprinting platform towards stratified articular cartilage tissue fabrication", pp. 2246-2252
  • Amer Dababneh and Ibrahim Ozbolat, 2013, "A virtual predictive environment for monitoring reliability and maintainability of printed circuit boards", pp. 2384-2393
  • Yin Yu and Ibrahim Ozbolat, 2013, "Cell viability characterization of bioprintable blood-vessel-like cellular channels towards 3D organ fabrication", pp. 2299-2304
  • Yin Yu and Ibrahim Ozbolat, 2013, "Bioprinting Induced Cell Damage In Cellular Micro-fluidic Channel Fabrication", Proceedings of The ASME 8th International Manufacturing Science And Engineering Conference
  • Howard Chen and Ibrahim Ozbolat, 2013, "Development of A Multi-arm Bioprinter For Hybrid Tissue Engineering", Proceedings of The ASME 8th International Manufacturing Science And Engineering Conference
  • Yin Yu and Ibrahim Ozbolat, 2013, "Direct Bioprinting of Perfusable Vascularized Tissues", Proceedings of International Conference on Biofabrication
  • Akm B. Khoda, Ibrahim Ozbolat and Bahattin Koc, 2012, "Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan", 2, pp. 571-577
  • Ibrahim Ozbolat, Bahattin Koc and Yaqin Deng, 2012, "Multi-directional blending for heterogeneous object modeling", 3, pp. 319-324
  • Ibrahim Ozbolat, A. K.M.B. Khoda and Baliattiu Koc, 2012, "Bioadditive manufacturing of hybrid tissue scaffolds for controlled release kinetics", 2, pp. 233-237
  • Ibrahim Ozbolat and B. Koc, 2012, "Multi-material blending for complex-shaped heterogeneous objects", pp. 221-225
  • A. K.M.B. Khoda, Ibrahim Ozbolat and B. Koc, 2012, "Spatially varying porosity with continuous path plan for hollowed tissue scaffolds", pp. 73-77
  • Ibrahim Ozbolat, A. K.M.B. Khoda, M. Marchany, J. A. Gardella and B. Koc, 2012, "Heterogeneous tissue scaffolds for spatiotemporally controlled release kinetics", pp. 79-84
  • Yahui Zhang, Howard Chen and Ibrahim Ozbolat, 2012, "Characterization of Printable Micro-fluidic Channels for Organ Printing"
  • Yahui Zhang, Omer Elgaali and Ibrahim Ozbolat, 2012, "Multi-functional hybrid tissue scaffolds", pp. 632-637
  • Yahui Zhang, Howard Chen and Ibrahim Ozbolat, 2012, "Printable Micro-fluidic Channels towards Organ Printing"
  • Ibrahim Ozbolat, Amer Debabneh, Omer Elgaali, Yahui Zhang, Timothy Marler and Steven Turek, 2012, "A model based enterprise approach in electronics manufacturing: Predictive environment for visualization of electromechanical virtual validation", pp. 3704-3708
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "Hybrid wound devices for spatiotemporally controlled release kinetics", 2, pp. 425-427
  • Bashir Khoda, Ibrahim Ozbolat and Bahattin Koc, 2011, "Modeling and fabrication of hollowed scaffolds with interconnected variational porosity architecture", 2, pp. 969-980
  • Ibrahim Ozbolat, 2011, "Path planning for functionally graded materials in hollow tissue scaffold printing", 3, pp. 49-53
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "Multi-directional material blending for heterogeneous object modeling"
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "3D engineered wound scaffolds for spatiotemporally controlled release kinetics"
  • A. K.M.B. Khoda, Ibrahim Ozbolat and Bahattin Koc, 2011, "A new Toolpath Planning in Solid Freeform Fabrication for Hollowed Objects"
  • Ibrahim Ozbolat and Bahattin Koc, 2011, "Continuous toolpath planning for 3D heterogeneous porous structures"
  • Ibrahim Ozbolat and Bahattin Koc, 2010, "Spatially Controlled Biomolecules in 3D Porous Structures"
  • Ibrahim Ozbolat, A. K.M.B. Khoda and Bahattin Koc, 2010, "Toolpath optimization in solid freeform modeling and fabrication of 3D porous structures"
  • Ibrahim Ozbolat and Bahattin Koc, 2009, "Computer-aided Bio-modeling of Micro-patterned Structures for Tissue Engineering"
  • Ibrahim Ozbolat, Bashir Khoda and Bahattin Koc, 2009, "Geometric Modeling of Complex Tissue Engineering Scaffolds with Controlled Porosity Distribution"

Other

  • Shantanab Dinda, Yang Wu and Ibrahim Ozbolat, 2018, "How to print a better human", Industrial and Systems Engineer, 50, (8), pp. 35-39
  • Ibrahim Ozbolat, 2015, "Three-dimensional printing of biological tissues"
  • Ibrahim Ozbolat and Howard Chen, 2013, "Manufacturing living things", Industrial Engineer, 45, (1), pp. 30-34

Research Projects

Honors and Awards

  • Hartz Family Career Development Professorship in Engineering, College of Engineering at Penn State University, 2017 - 2020
  • Honorable Mention Award, Society for Biomaterials, 2018
  • The International Outstanding Young Researcher in Freeform and Additive Manufacturing Award, International Society of Solid Freeform Fabrication, 2015
  • Dr. Hamed K. Eldin Outstanding Early Career IE in Academia Award, Institute of Industrial Engineers, 2015
  • Who’s Who in America, Marquis Who’s Who, 2015
  • Chao and Trigger Young Manufacturing Engineer Award, American Society of Mechanical Engineers, 2014
  • Tau Pi Sigma Gold Medal, American Society of Mechanical Engineers, 2014
  • CAREER Award, National Science Foundation, 2014
  • Outstanding Young Manufacturing Engineer Award, Society of Manufacturing Engineers, 2014
  • Selected Article in 2013 Highlights of Biofabrication, Biofabrication Journal, 2013
  • Start-up Launch Award, The University of Iowa, 2013
  • Best Manufacturing and Design Track Paper Award, Institute of Industrial Engineers, 2013
  • Innovations in Teaching with Technology Award, The University of Iowa, 2013
  • Faculty Leadership Award, Center for Computer Aided Design at The University of Iowa, 2013
  • Innovations in Teaching with Technology Award, The University of Iowa, 2012
  • 3rd Prize Recipient at the Engineering Graduate Student Poster Competition, University at Buffalo, 2010
  • Winner at Industrial & Systems Engineering Department Poster Competition, University at Buffalo, 2010
  • Fellowship for Undergraduate Study, Turkish National Education Foundation, 2002 - 2006
  • Bronze Medal at the 3rd National Mathematics Olympics, The Scientific & Technological Research Council of Turkey, 1998
  • TUSEB Incentive (Presidential) Award, Health Institutes of Turkey, November 2022

Service

Service to Penn State:

Service to External Organizations:

 


 

About

The Penn State Department of Engineering Science and Mechanics (ESM) is an internationally distinguished department that is recognized for its globally competitive excellence in engineering and scientific accomplishments, research, and educational leadership.

Our Engineering Science program is the official undergraduate honors program of the College of Engineering, attracting the University’s brightest engineering students. We also offer graduate degrees in ESM, engineering mechanics, engineering at the nano-scale, and an integrated undergraduate/graduate program.

Department of Engineering Science and Mechanics

212 Earth and Engineering Sciences Building

The Pennsylvania State University

University Park, PA 16802

Phone: 814-865-4523