Xiaole Mao

Xiaole Mao
Ph.D. Candidate
Biofunctionalized Nano-Electro-Mechanical-Systems (BioNEMS) Laboratory
Department of Engineering Science and Mechanics
Pennsylvania State University
212 Earth-Engineering Sciences Building
University Park, PA 16802-6812
Tel: 1-814-865-0661
Fax: 1-814-865-9974
Email: xum101@psu.edu
Research Interests
- Lab on a Chip
- Microfluidics
- Optofluidics
- Plasmonics
Education
- Ph.D. in Bioengineering, expected in Aug 2010, Pennsylvania State University, University Park, USA (advisor:Prof. Tony Jun Huang)
- M.S. in Biological Engineering, Dec 2004; University of Arkansas, Fayetteville, USA.(advisor:Prof. Yanbin Li)
- B.E. in Biotechnology, Jun 2002; Southern Yangtze University, China.
Awards and Honors
- Outstanding Poster Award, ASME Society-Wide Micro/Nano Technology Forum at IMECE 2009
- The Pennsylvania State University Inventor Incentive Award, 2009
- Graduate Student Travel Award, MicroTAS, 2008
- Innovation Award at Penn State ESM Today Graduate Research Symposium (Highest Award), 2008
- 1st Place Hewlett-Packard Best Student Paper Award by Hewlett-Packard & American Society of Mechanical Engineers at IMECE 2006
- The Huck Institutes of the Life Sciences Fellowship, 2005-2006
- 2nd Place Award in the University of Arkansas Gamma Sigma Delta Student Research Presentation Competition, 2004
Media Coverage on My Research
"Liquid flow controls tunable microlens", Optics.org (2009)
http://optics.org/cws/article/research/39219
"Liquid Lens Creates Tiny Flexible Laser On a Chip", US News (2009)
"Liquid Lens That Can Focus and Direct Light at Will", Azooptics (2009)
http://www.azooptics.com/Details.asp?newsID=4301
"Scientists create liquid lens on a chip", MarketWatch (2009)
http://www.marketwatch.com/story/scientists-create-liquid-lens-on-a-chip?dist=msr_1
"Optofluidics Emerges from the Laboratory", Photonics Spectra Feb Issue (2009)
http://www.photonics.com/Content/ReadArticle.aspx?ArticleID=32250
"Journal to feature scientific art from Penn State engineers" (2007)
http://www.engr.psu.edu/NewsEvents/newsdetail.aspx?NewsID=5666&NewsDate=10/9/2007#5666
Front cover article on journal Lab on a Chip, Oct Issue (2007)
http://www.rsc.org/delivery/_ArticleLinking/DisplayArticleForFree.cfm?doi=b713948a&JournalCode=LC
Journal Publications
- Xiaole Mao, Bala Krishna Juluri, Michael Ian Lapsley, Zackary S. Stratton and Tony Jun Huang, Milliseconds Microfluidic Chaotic Bubble Mixer, Microfluidics and Nanofluidics, 2009, DOI: 10.1007/s10404‐009‐0496‐4.
- Michael Ian Lapsley, Sz-Chin Steven Lin, Xiaole Mao, and Tony Jun Huang, An In-Plane, Variable Optical Attenuator Using a Fluid-Based Tunable Reflective Interface, Applied Physics Letters, 2009, Applied Physics Letters, 2009, 95, 083507.
- Jinjie Shi, Daniel Ahmed, Xiaole Mao, Sz-Chin Steven Lin, and Tony Jun Huang, Acoustic Tweezers: Patterning Cells and Microparticles Using Standing Surface Acoustic Waves (SSAW), Lab on a Chip, 2009, 9, 2890 ‐ 2895.
- Daniel Ahmed, Xiaole Mao, Jinjie Shi, Bala Krishna Juluri and Tony Jun Huang, A Millisecond Micromixer via Single-Bubble-Based Acoustic Streaming, Lab on a Chip, 2009, 9, 2738 ‐ 2741.
- Daniel Ahmed, Xiaole Mao, Bala Krishna Juluri and Tony Jun Huang, A Fast Microfluidic Mixer Based on Acoustically Driven Sidewall-Trapped Microbubbles, Microfluidics and Nanofluidics, 2009, DOI: 10.1007/s10404-009-0444-3, in press.
- Xiaole Mao, Sz-Chin Steven Lin, Michael Ian Lapsley, Jinjie Shi, Bala Krishna Juluri, and Tony Jun Huang, Tunable Liquid Gradient Refractive Index (L-GRIN) Lens with Two Degrees of Freedom, Lab on a Chip, 2009, 9, 2050 - 2058.
- Xiaole Mao, Sz-Chin Steven Lin, Cheng Dong, and Tony Jun Huang, Single-Layer Planar On-Chip Flow Cytometer Using Microfluidic Drifting Based Three-Dimensional (3D) Hydrodynamic Focusing, Lab on a Chip, 2009, 9, 1583 - 1589.
- Jinjie Shi, Xiaole Mao, Daniel Ahemd, Thomas R. Walker, and Tony Jun Huang. Focusing microparticles in a microfluidic channel with standing surface acoustic waves (SSAW). Lab on a Chip, 2008, 8, 221.
- Yuebing Zheng, Bala Krishna Juluri, Xiaole Mao, Daniel Ahemd, Ashley Colletti, and Tony Jun Huang. Systematic Investigation of Localized Surface Plasmon Resonance of Long-Range Ordered Au Nanodisk Arrays. Journal of Applied Physics, 2008, 103, 014308.
- Xiaole Mao, and Tony Jun Huang. Focusing Fluids and Light in Micro/Nano Scale – Enabling Technologies for Single-Particle Detection. IEEE Nanotechnology Magazine, 2008, 2, 22.
- Xiaole Mao, John R. Waldeisen, and Tony Jun Huang. “Microfluidic Drifting” - Implementing Three-Dimensional Hydrodynamic Focusing with a Single-Layer Planar Microfluidic Device. Lab on a Chip, 2007, 7, 1260. (Featured on Journal Cover)
- Xiaole Mao, John R. Waldeisen, Bala Krishna Juluri, and Tony Jun Huang. Hydrodynamically Tunable Optofluidic Cylindrical Microlens. Lab on a Chip, 2007, 7, 1303.
- Xiaole Mao, Liju Yang, Xiaole Su, and Yanbin Li. A Nanoparticle Amplification Based Quartz Crystal Microbalance DNA Sensor for Detection of Escherichia coli O157:H7. Biosensors & Bioelectronics, 2006, 21, 1178.
Conference Presentations
- Xiaole Mao, S.-C. Steven Lin, Michael I. Lapsley, and Tony Jun Huang. An Fully-integrated, High-throughput, Multi-parameter flow cyotmetry chip for point-of-care diagnostics. ASME International Mechanical Engineering Congress & Exposition, Lake Buena Vista, FL, 2009.
- Xiaole Mao, S.-C. Steven Lin, Michael I. Lapsley, and Tony Jun Huang. A Fully‐Integrated Flow Cytometry Chip Fabricated with Single‐Step Soft‐Lithography. BMES Annual Fall Meeting, Pittsburgh, PA, 2009.
- Xiaole Mao, S.-C. Steven Lin, Michael Lapsley, Jinjie Shi, Bala Krishna Juluri, and Tony Jun Huang. A Tunable Optofluidic Microlens Based on Gradient Refractive Index. Conference on Lasers and Electro Optics (CLEO), Baltimore, MD, 2009.
- Xiaole Mao-,S.-C. Steven Lin, and Tony Jun Huang. High Throughput Micro Flow Cytometry System Using “Microfluidic Drifting” Based Three‐dimensional (3D) Hydrodynamic Focusing. Transducer conference, Denver, Colorado, 2009.
- Xiaole Mao, Bala Krishna Juluri, Michael Lapsley, and Tony Jun Huang, A Fast Micromixer and Microreactor Based on Dynamic Self-Assembly of Monodisperse Microbubbles, ASME International Mechanical Engineering Congress & Exposition, Boston, MA, 2008.
- Xiaole Mao, Michael Lapsley, John Waldeisen, and Tony Jun Huang, An Opto-Fluidic Hybrid System for Miniaturized Flow Cytometry: Focusing of Cells and Light on Microscale, ASME International Mechanical Engineering Congress & Exposition, Boston, MA, 2008.
- Xiaole Mao, John R. Waldeisen, and Tony Jun Huang. “Microfluidic Drifting” – Implementing Three-Dimensional Hydrodynamic Focusing with a Two-Dimensional Microfluidic Device. BMES Annual Fall Meeting, Los Angeles, CA 2007.
- Xiaole Mao, Sung Yang, and Jeffrey D. Zhan. Experimental Demonstration and Numerical Simulation of Organic-Aqueous Liquid Extraction Enhanced by Droplet Formation in a Microfluidic Channel. ASME International Mechanical Engineering Congress & Exposition, Chicago, IL, 2006.
Book Chapters
- Xiao Mao, Zackery S. Stratton, and Tony Jun Huang. Optofluidic Imaging Elements. In: Schmidt, H. and Hawkins, A. (Ed.),Handbook of Optofluidics, CRC Press.
- Xiaole Mao, Tony Jun Huang, and Chih-Ming Ho. The application of microfluidics and MEMS/NEMS in molecular diagnostics. In: Grody, W.W., Nakamura, R.M., Strom, C. (Ed.), Handbook of Molecular Diagnostics, Elsevier.
- Jeffrey D. Zahn, Reddy Varum, and Xiaole Mao. Lab on a Chip Devices for Sample Extractions. In: Li, D. (Ed.), Encyclopedia of Microfluidics and Nanofluidics, Springer-Verlag Berlin Heidelberg.
Patents
- Xiaole Mao and Tony Jun Huang. On‐Chip 3D Hydrodynamic Focusing and High‐Throughput Detection of Microparticles.(U.S. Provisional Patent, PSU Inv. Disc. No. 2009‐3584)
- Xiaole Mao and Tony Jun Huang. Tunable Liquid Gradient Refractive Index Lens Device. (U.S. Provisional Patent, PSU Inv. Disc. No. 2009‐3580)
- Xiaole Mao and Tony Jun Huang. Nucleic Acid Sequencing. (U.S. Provisional Patent, PSU Inv. Disc. No. 2008‐3439)
- Xiaole Mao and Tony Jun Huang. Three‐Dimensional (3D) Hydrodynamic Focusing Using a Mircofluidic Device. (U.S. Patent Pending, PSU Inv. Disc. No. 2007‐3370)
Teaching Experience
- Engineering Science 496A – Nanotransformations: The Social, Human and Ethical Impacts of Nanotechnology, 2009 (guest lectures)
Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.
- E SC 481 – Elements of Nano/Micro Electromechanicalsystems (MEMS/NEMS) Processing and Design (Fall 2009) (guest lectures)
Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.
- E SC 581 – Nano/Micro Electromechanicalsystems (MEMS/NEMS) Processing and Design (Spring 2009) (guest lectures)
Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.
- E SC 481 – Elements of Nano/Micro Electromechanicalsystems (MEMS/NEMS) Processing and Design (Fall 2008) (guest lectures)
Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.
- E SC 481 – Elements of Nano/Micro Electromechanicalsystems (MEMS/NEMS) Processing and Design (Fall 2007) (guest lectures)
Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.
- Mentor, National Nanotechnology Infrastructure Network Research Experience for Undergraduates Program (NNIN‐REU), Summer 2007
- Teaching Assistant, Department of Chemical Engineering, Penn State University, Fall 2006


