Xiaole Mao


Xiaole Mao
Ph.D. Candidate

Biofunctionalized Nano-Electro-Mechanical-Systems (BioNEMS) Laboratory
Department of Engineering Science and Mechanics
Pennsylvania State University
212 Earth-Engineering Sciences Building
University Park, PA 16802-6812

Tel: 1-814-865-0661
Fax: 1-814-865-9974

Email: xum101@psu.edu


Research Interests

  • Lab on a Chip
  • Microfluidics
  • Optofluidics
  • Plasmonics

Education

  • Ph.D. in Bioengineering, expected in Aug 2010, Pennsylvania State University, University Park, USA (advisor:Prof. Tony Jun Huang)
  • M.S. in Biological Engineering, Dec 2004; University of Arkansas, Fayetteville, USA.(advisor:Prof. Yanbin Li)
  • B.E. in Biotechnology, Jun 2002; Southern Yangtze University, China.

Awards and Honors

  • Outstanding Poster Award, ASME Society-Wide Micro/Nano Technology Forum at IMECE 2009
  • The Pennsylvania State University Inventor Incentive Award, 2009
  • Graduate Student Travel Award, MicroTAS, 2008
  • Innovation Award at Penn State ESM Today Graduate Research Symposium (Highest Award), 2008
  • 1st Place Hewlett-Packard Best Student Paper Award by Hewlett-Packard & American Society of Mechanical Engineers at IMECE 2006
  • The Huck Institutes of the Life Sciences Fellowship, 2005-2006
  • 2nd Place Award in the University of Arkansas Gamma Sigma Delta Student Research Presentation Competition, 2004

Media Coverage on My Research

"Liquid flow controls tunable microlens", Optics.org (2009)

http://optics.org/cws/article/research/39219

"Liquid Lens Creates Tiny Flexible Laser On a Chip", US News (2009)

http://www.usnews.com/articles/science/2009/05/12/liquid-lens-creates-tiny-flexible-laser-on-a-chip.html

"Liquid Lens That Can Focus and Direct Light at Will", Azooptics (2009)

http://www.azooptics.com/Details.asp?newsID=4301

"Scientists create liquid lens on a chip", MarketWatch (2009)

http://www.marketwatch.com/story/scientists-create-liquid-lens-on-a-chip?dist=msr_1

"Optofluidics Emerges from the Laboratory", Photonics Spectra Feb Issue (2009)

http://www.photonics.com/Content/ReadArticle.aspx?ArticleID=32250

"Journal to feature scientific art from Penn State engineers" (2007)

http://www.engr.psu.edu/NewsEvents/newsdetail.aspx?NewsID=5666&NewsDate=10/9/2007#5666

Front cover article on journal Lab on a Chip, Oct Issue (2007)

http://www.rsc.org/delivery/_ArticleLinking/DisplayArticleForFree.cfm?doi=b713948a&JournalCode=LC

Journal Publications

  1. Xiaole Mao, Bala Krishna Juluri, Michael Ian Lapsley, Zackary S. Stratton and Tony Jun Huang, Milliseconds Microfluidic Chaotic Bubble Mixer, Microfluidics and Nanofluidics, 2009, DOI: 10.1007/s10404‐009‐0496‐4.
  2. Michael Ian Lapsley, Sz-Chin Steven Lin, Xiaole Mao, and Tony Jun Huang, An In-Plane, Variable Optical Attenuator Using a Fluid-Based Tunable Reflective Interface, Applied Physics Letters, 2009, Applied Physics Letters, 2009, 95, 083507.
  3. Jinjie Shi, Daniel Ahmed, Xiaole Mao, Sz-Chin Steven Lin, and Tony Jun Huang, Acoustic Tweezers: Patterning Cells and Microparticles Using Standing Surface Acoustic Waves (SSAW), Lab on a Chip, 2009, 9, 2890 ‐ 2895.
  4. Daniel Ahmed, Xiaole Mao, Jinjie Shi, Bala Krishna Juluri and Tony Jun Huang, A Millisecond Micromixer via Single-Bubble-Based Acoustic Streaming, Lab on a Chip, 2009, 9, 2738 ‐ 2741.
  5. Daniel Ahmed, Xiaole Mao, Bala Krishna Juluri and Tony Jun Huang, A Fast Microfluidic Mixer Based on Acoustically Driven Sidewall-Trapped Microbubbles, Microfluidics and Nanofluidics, 2009, DOI: 10.1007/s10404-009-0444-3, in press.
  6. Xiaole Mao, Sz-Chin Steven Lin, Michael Ian Lapsley, Jinjie Shi, Bala Krishna Juluri, and Tony Jun Huang, Tunable Liquid Gradient Refractive Index (L-GRIN) Lens with Two Degrees of Freedom, Lab on a Chip, 2009, 9, 2050 - 2058.
  7. Xiaole Mao, Sz-Chin Steven Lin, Cheng Dong, and Tony Jun Huang, Single-Layer Planar On-Chip Flow Cytometer Using Microfluidic Drifting Based Three-Dimensional (3D) Hydrodynamic Focusing, Lab on a Chip, 2009, 9, 1583 - 1589.
  8. Jinjie Shi, Xiaole Mao, Daniel Ahemd, Thomas R. Walker, and Tony Jun Huang. Focusing microparticles in a microfluidic channel with standing surface acoustic waves (SSAW). Lab on a Chip, 2008, 8, 221.
  9. Yuebing Zheng, Bala Krishna Juluri, Xiaole Mao, Daniel Ahemd, Ashley Colletti, and Tony Jun Huang. Systematic Investigation of Localized Surface Plasmon Resonance of Long-Range Ordered Au Nanodisk Arrays. Journal of Applied Physics, 2008, 103, 014308.
  10. Xiaole Mao, and Tony Jun Huang. Focusing Fluids and Light in Micro/Nano Scale – Enabling Technologies for Single-Particle Detection. IEEE Nanotechnology Magazine, 2008, 2, 22.
  11. Xiaole Mao, John R. Waldeisen, and Tony Jun Huang. “Microfluidic Drifting” - Implementing Three-Dimensional Hydrodynamic Focusing with a Single-Layer Planar Microfluidic Device. Lab on a Chip, 2007, 7, 1260. (Featured on Journal Cover)
  12. Xiaole Mao, John R. Waldeisen, Bala Krishna Juluri, and Tony Jun Huang. Hydrodynamically Tunable Optofluidic Cylindrical Microlens. Lab on a Chip, 2007, 7, 1303.
  13. Xiaole Mao, Liju Yang, Xiaole Su, and Yanbin Li. A Nanoparticle Amplification Based Quartz Crystal Microbalance DNA Sensor for Detection of Escherichia coli O157:H7. Biosensors & Bioelectronics, 2006, 21, 1178.

Conference Presentations

  1. Xiaole Mao, S.-C. Steven Lin, Michael I. Lapsley, and Tony Jun Huang. An Fully-integrated, High-throughput, Multi-parameter flow cyotmetry chip for point-of-care diagnostics. ASME International Mechanical Engineering Congress & Exposition, Lake Buena Vista, FL, 2009.
  2. Xiaole Mao, S.-C. Steven Lin, Michael I. Lapsley, and Tony Jun Huang. A Fully‐Integrated Flow Cytometry Chip Fabricated with Single‐Step Soft‐Lithography. BMES Annual Fall Meeting, Pittsburgh, PA, 2009.
  3. Xiaole Mao, S.-C. Steven Lin, Michael Lapsley, Jinjie Shi, Bala Krishna Juluri, and Tony Jun Huang. A Tunable Optofluidic Microlens Based on Gradient Refractive Index. Conference on Lasers and Electro Optics (CLEO), Baltimore, MD, 2009.
  4. Xiaole Mao-,S.-C. Steven Lin, and Tony Jun Huang. High Throughput Micro Flow Cytometry System Using “Microfluidic Drifting” Based Three‐dimensional (3D) Hydrodynamic Focusing. Transducer conference, Denver, Colorado, 2009.
  5. Xiaole Mao, Bala Krishna Juluri, Michael Lapsley, and Tony Jun Huang, A Fast Micromixer and Microreactor Based on Dynamic Self-Assembly of Monodisperse Microbubbles, ASME International Mechanical Engineering Congress & Exposition, Boston, MA, 2008.
  6. Xiaole Mao, Michael Lapsley, John Waldeisen, and Tony Jun Huang, An Opto-Fluidic Hybrid System for Miniaturized Flow Cytometry: Focusing of Cells and Light on Microscale, ASME International Mechanical Engineering Congress & Exposition, Boston, MA, 2008.
  7. Xiaole Mao, John R. Waldeisen, and Tony Jun Huang. “Microfluidic Drifting” – Implementing Three-Dimensional Hydrodynamic Focusing with a Two-Dimensional Microfluidic Device. BMES Annual Fall Meeting, Los Angeles, CA 2007.
  8. Xiaole Mao, Sung Yang, and Jeffrey D. Zhan. Experimental Demonstration and Numerical Simulation of Organic-Aqueous Liquid Extraction Enhanced by Droplet Formation in a Microfluidic Channel. ASME International Mechanical Engineering Congress & Exposition, Chicago, IL, 2006.

Book Chapters

  1. Xiao Mao, Zackery S. Stratton, and Tony Jun Huang. Optofluidic Imaging Elements. In: Schmidt, H. and Hawkins, A. (Ed.),Handbook of Optofluidics, CRC Press.
  2. Xiaole Mao, Tony Jun Huang, and Chih-Ming Ho. The application of microfluidics and MEMS/NEMS in molecular diagnostics. In: Grody, W.W., Nakamura, R.M., Strom, C. (Ed.), Handbook of Molecular Diagnostics, Elsevier.
  3. Jeffrey D. Zahn, Reddy Varum, and Xiaole Mao. Lab on a Chip Devices for Sample Extractions. In: Li, D. (Ed.), Encyclopedia of Microfluidics and Nanofluidics, Springer-Verlag Berlin Heidelberg.

Patents

  1. Xiaole Mao and Tony Jun Huang. On‐Chip 3D Hydrodynamic Focusing and High‐Throughput Detection of Microparticles.(U.S. Provisional Patent, PSU Inv. Disc. No. 2009‐3584)
  2. Xiaole Mao and Tony Jun Huang. Tunable Liquid Gradient Refractive Index Lens Device. (U.S. Provisional Patent, PSU Inv. Disc. No. 2009‐3580)
  3. Xiaole Mao and Tony Jun Huang. Nucleic Acid Sequencing. (U.S. Provisional Patent, PSU Inv. Disc. No. 2008‐3439)
  4. Xiaole Mao and Tony Jun Huang. Three‐Dimensional (3D) Hydrodynamic Focusing Using a Mircofluidic Device. (U.S. Patent Pending, PSU Inv. Disc. No. 2007‐3370)

Teaching Experience

  • Engineering Science 496A – Nanotransformations: The Social, Human and Ethical Impacts of Nanotechnology, 2009 (guest lectures)

Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.

Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.

Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.

Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.

Gave lectures on introduction to microfluidics, micro/nanofabrication, and miniaturized biomedical devices.

  • Mentor, National Nanotechnology Infrastructure Network Research Experience for Undergraduates Program (NNIN‐REU), Summer 2007
  • Teaching Assistant, Department of Chemical Engineering, Penn State University, Fall 2006

Professional Memberships

Reviewer for Journals

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